肝门静脉阻力与食管静脉曲张再出血的关系

Assessment of the Relationships between Hepatic Venous Pressure Gradient, Portal Vascular Resistance and the Risk of Recurrent Esophageal Variceal Bleeding

目的 探讨肝门静脉阻力与食管静脉曲张再出血之间的关系。方法 对 2 1例食管静脉曲张 (EV)的肝硬化并门静脉高压患者 ,测其肝静脉压梯度 (HVPG) ,对其中之 18例相继测门静脉血管阻力 (PVR) ,探讨两值与 EV再出血之关系。分手术组 (n=10 )和介入组 (n=11) ,用 Seldinger法经肝右静脉测 HVPG;参照 Moriyasu法测算 PVR。结果 HVPG和 PVR两值在手术组显著低于介入组。结论 EV再出血几乎均发生于两值的高值者。HVPG测定简易可行 ,安全 ,有预测 EV再出血的价值 ,PVR测定难度大 ,但有量化门脉高压程度 ,较 HVPG更精确。

Objective To explore the relationships between hepatic venous pressure gradient,portal vascular resistance and the risk of recurrent esophageal variceal bleeding.Methods 21cases of liver cirrhosis with portal hypertension were divided into operative group (n=10) and intervention group (n=11).HVPG according Seldinger method and PVR according to Moriyasu method were carried out to analyze the relationships.Results Both values in operative groups were significantly lower than those in intervention group.Conclusion The HVPG was convenient and safe and predictive of REVB,while PVR could evaluate quantitatively the degree portal hypertension,and more precise in evaluation for risk of REVB.