骨髓基质细胞诱导为雪旺细胞修复周围神经缺损

Bone marrow stroma cells differentiate into Schwann cells for regeneration of peripheral nerve

骨髓基质细胞(bonemarrowstromacells,BMSCs)是来源于骨髓基质的一种间充质细胞,来源丰富,可以解决雪旺细胞来源不足的缺点。骨髓基质细胞在体外诱导为神经细胞,诱导后进行培养。用特异性抗体检测细胞内蛋白。(1)利用新方法制作组织工程化的神经,为临床解决失神经肌肉的不可逆萎缩提供新的思路。(2)利用细胞诱导的方法,为组织工程化神经的临床应用提供研究基础。

Bone marrow stroma cells are derived of bone marrow and can be used to solve t he issue of lake of Schwann cells. The bone marrow stroma cells were induced to differentiate into nerve cells and cultivated in vitro.Then histochemistry stain s were performed.(1)To make tissue-engineering nerve by finding a new way.(2)To use the induction method to provide basic research for clinical use.