黄芪注射液联合刺五加注射液治疗冠心病心绞痛疗效观察

The Observation of Efficacy of Huangqi Injection in Combination with Ciwujia Injection in the Treatment of Coronary Heart Disease Angina Pectoris.

目的:联合应用黄芪注射液和刺五加注射液治疗冠心病心绞痛,观察疗效及不良反应。方法:对100例冠心病心绞痛病人随机分成两组,对照组给予常规应用硝酸酯类、β受体阻滞剂、钙离子拮抗剂、肠溶阿斯匹林和极化液等治疗,治疗组在常规治疗的基础上给予黄芪注射液20mL+5％GS250mL和刺五加注射液40mL+5％GS250mL分步静滴,每日1次,疗程2周,观察两组患者用药前后心绞痛、心电图、血流变改变情况及不良反应。结果:治疗组心绞痛、心电图及血流变改变情况较对照组显著(分别为P<0.01,P<0.05,P<0.01),总有效率治疗组为94％,与对照组(56%)比较有显著差异(P<0.01),未见副反应。结论:黄芪注射液联合刺五加注射液治疗冠心病心绞痛疗效显著,无不良反应。

Objective: To investigate the effect of Huangqi injection in combination with Ciwujia injection in the treatment of coronary heart disease(CHD) angina pectoris.Methods: 100 patients with angina pectoris were randomly divided into two groups.The control group were outinely treated with Nitroglycerin,β-blocker,calcium channel blocker (CCB) , Aspirin,polariz liquid. On the base of normal treatment, the treatment group was injected with Huangqi 20mL+ 5%GS250mL 1/d and Ciwujia 40mL + 5%GS250mL 1/ d for two weeks. The changs of angina pectoris, electrocardiogram(ECG) , blovel change and adverse reaction of the drug were observed before and after treatment.Result:The treatment group in angina pectoris, ECG and blovel change had better effects than the control group( P<0.01,P<0.05,P<0.01 respectively) . The total effective rate of treatment group was 94% , compared with the control group (56%).There was significant difference (P<0.01).No side effects were observed. Conclusion:Huangqi injection in combination with Ciwujia injection are effective in the treatment of CHD angina pectoris. No adverse reaction were found.