口服支链氨基酸治疗肝硬化低蛋白血症多中心总结

The effect of oral branched amino acid for cirhotic patient with low serum protein.

为验证口服支链氨基酸治疗肝硬化低蛋白血症的疗效,将149例患者随机分为两组,A组口服支链氨基酸,B组口服复方氨基酸胶囊,疗程9周。结果表明:A组血清白蛋白水平由治疗前(32.25±3.11)g/dl升高到(37.61±5.13)g/dl(P<0.05);B组血清白蛋白由治疗前(32.12±2.04)g/dl升高到(36.64±4.66)g/dl(P<0.05),两组对比,支链氨基酸组血清白蛋白升幅明显高于对照组。两组均未发生严重不良反应。因此,支链氨基酸是一种安全有效的提升肝病患者白蛋白水平的药品。

To evaluate the effect of oral branched amino acid for cirrhotic patients with low serum protein 149 patients were randomized into two groups:group A(n= 99)were given branched amino acid 4.74g tid; group B (n = 50) were given compound amino acid 3.5g tid. The treatment duration was 9 weeks. The results show that both branched amino acid and compound amino acid can effectively increase serum levels of total protein, but branched amino acid is better in increasing serum albumin level than compound amino acid.