粪便检查对早期胃肠道恶性肿瘤筛查的研究进展

近年来,随着环境污染与食品安全问题的日益严峻,胃肠道恶性肿瘤的发病率逐年升高,在全球范围内已位居各类恶性肿瘤前列。在我国胃肠道恶性肿瘤的死亡率居恶性肿瘤首位。早期发现、早期诊断、早期治疗对于延长患者生存时间、降低死亡率具有非常重要的意义[1]。消化内镜和病理组织活检是诊断的金标准,但由于有创伤、价格昂贵等因素,局限了在胃肠道肿瘤的筛查的作用。随着现代免疫学和分子生物学技术的进步,粪便检查成为人们筛查早期胃肠道肿瘤新的手段。现就粪便检查对早期胃肠道肿瘤筛查的研究进展做一综述。

With the environmental pollution and food safety issues becoming increasingly serious, the morbidity of gastrointestinal cancer has been increasing year by year in recent years, which has been among the various malignancies in the global scope. The mortality of gastrointestinal cancer in our country ranks first among the malignant tumors. Early detection, early diagnosis and early treatment are of great significance to prolong the survival time and reduce the mortality of patients. Endoscopic and pathological biopsy is the gold standard for diagnosis, but due to trauma, high price and other factors, the screening effect in gastrointestinal cancer is limited. With the development of modern immunology and molecular biology, stool examination has become a new tool for the early detection of gastrointestinal cancer. Review on the research progress in the early stage of gastrointestinal cancer screening Is writed.