气管插管行呼吸支持并洗胃对抢救重度有机磷中毒的临床研究

The Clinical Research of Endotracheal Intubation Respiratory Support and Gastric Lavage for Rescuing Severe Organophosphate Poisoning

目的:探究气管插管行呼吸支持并洗胃对抢救重度有机磷中毒患者的效果。方法:选取2015年6月-2017年2月在本院接受治疗的50例重症有机磷中毒患者按照随机原则分为A、B二组。A组采用气管插管行呼吸支持并洗胃方式,B组患者采用气管插管后自主呼吸并洗胃方式。另从2014年6月-2015年5月抽取25例重症有机磷中毒患者作为C组,不进行气管插管直接洗胃。对比三组患者疗效。结果:A、B两组患者抢救成功率均为100%,C组患者抢救成功率为88%。A组并发症率为4%,明显低于其他两组(P<0.05)。A组住院费用及住院时间与B组差异明显(P<0.05),与C组的差异更加明显(P<0.01)。结论:对重度有机磷中毒患者采用气管插管行呼吸支持并洗胃具有较高的抢救成功率及安全性。

Objective:To explore the effect of tracheal intubation and gastric lavage on patients of severe organophosphorus poisoning with respiratory support. Methods:Fifty patients with severe organophosphorus-poisoned patients who had been treated in our hospital from June 2015 to February 2017 were randomly divided into Group A treated with tracheal intubation and gastric lavage and Group B patients were treated with endotracheal intubation and gastric lavage. 25 patients with severe organophosphorus-poisoned patients who had been treated in our hospital from June 2015 to February 2017 were enrolled in group C treated with only gastric lavage. The effect of treatment was compared among three groups. Results:The success rate was 100% in group A the same as group B,while it was 88% in Group C. The rate of complication in group A was significantly lower than the other two groups(P<0.05). Expenses and the time of hospitalization in group A were significantly lower than those of group B(P<0.05),and significantly lower than that in C group(P<0.01). Conclusion:The treatment of gastric lavage with tracheal intubation for respiratory support will increase the successful rescue rate and is safety for severe organophosphate poisoning.