2[5]Pinducciu C,Borgonovo C,Arezzo A,et al.Toxic thyroid adenoma:absence of DNA mutations of the TSH receptor and Gs alpha[J].Eur J Endocirnol,1998,138(1):37-40.
3[6]Bahn RS,Dutton CM,Heufelder AE,et al.A genomic point mutation in the extracelluar domain of the thyrotropin receptor in patients with Grave's ophthalmopathy[J].J Clin Endocrinol Metab,1994,78(2):256-260.
4[7]Zhang ML,Sugawa H,Kosugi S,et al.Constitutive activation of the thyrotropin receptor by deletion of a protion of the extracellular domain[J].Biochen Biophys Res Commun,1995,211(1):205-210.
5[8]Lavard L,Sehested A,Brock Jacobsen B,et al.Long-term follow-up of infant with thyrotoxicosis due to germline mutation of the TSH receptor gene (Met 453 Thy)[J].Horm Res,1999,54(1):43-46.
6[9]Gu WX,Du GG,Kopp P,et al.The thyrotropin(TSH) receptor transmembrane domain mutation (Pro 556 Leu)in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding[J].Endocrinology,1995,136(7):3146-3153.
7[10]Clifton BRJ,Gregory JW,Ludgate M,et al.Two novel mutations in the thyrotropin(TSH) receptor gene in a child with resistance to TSH[J].J Clin Endocrinol Metab,1997,84(4):1094-1100.
8[11]Biebermann H,Schoneberg T,Krude H,et al.Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism[J].J Clin Endocrinol Metab,1997,82(10):3471-3480..
9[1]Parma J,Duprez L,Van-Sande J,et al.Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas[J].Nature,1993,14(6447):649-651.
10[2]Holzapfel HP,Fuhrer D,Wonerow P,et al.Identification of constitutively activating somatic thyrotropin receptor mutations in a subset of toxic multinodular goiters[J].J Clin Endocrinol Metab,1997,82 (12):4229-4233.
