辽阳地区生鲜乳中β-内酰胺类药物残留情况调查

Condition survey of the β-lactam drugs residual in fresh milk from Liaoyang District

本研究抽取辽阳市奶牛饲养场牛奶样品共25批次,通过超高效液相色谱-串联质谱法(UPLC-MS/MS),对其进行阿莫西林、氨苄西林、头孢氨苄、青霉素、苯唑西林和氯唑西林6种β-内酰胺类药物残留的检测。每批样品做2个平行样,同时在空白牛奶中添加10 ng/g的6种β-内酰胺类药物进行回收率试验,检测结果得出空白样品的6种药物添加回收率为79%~92%,25批牛奶样品其6种β-内酰胺酶类药物残留量均符合规定。此次调查可为辽阳市的生鲜乳质量安全监测提供数据支持。

25 batches of fresh milk were taken from local farms to test the residue of six kinds of ?-lactam drugs such as amoxicillin, ampicillin, cefalexin, penicillin, oxacillin and cloxacil-lin in the milk by ultra high performance liquid chromatography - tandem mass spectrometry(UPLC-MS/MS). Two parallel samples were taken from each batch and 10 ng/g of these six ?-lactam drugs were added in the pure milk simultaneously to conduct an experiment of recovery rate. The results indi-cated that the recovery rate was 79%~92% and the amount of the ?-lactam drugs in the 25 batches of fresh milk met the requirement. This survey will provide the fresh milk quality monitoring of our city with data support.