中医药治疗非酒精性脂肪肝病临床研究进展

Research Progress of Traditional Chinese Medicine in Treatment of Nonalcoholic Fatty Liver Disease

非酒精性脂肪性肝病(NAFLD)是一种与胰岛素抵抗和遗传易感性密切相关的代谢应激性肝损伤。现代医学对NAFLD缺乏有效的治疗方法,实验药理研究及临床疗效观察均已证实,中医药在防治NAFLD方面有一定的优势。文章就近年来NAFLD病因病机的研究,单味药、复方以及中成药实验和临床研究成果进行了归纳和总结,以期深化对NAFLD的认识以及提升该病的防治策略。

Non-alcoholic fatty liver disease(NAFLD)is a type of hepatic injury caused by metabolic stress,and the disease is closely related to insulin resistance and genetic susceptibility.Numerous pharmacological studies have demonstrated that many single or compound preparations of Chinese medicine can achieve satisfactory curative effect and possess unique advantages in prevention and treatment of NAFLD.This paper summarizes the study on pathology of NAFLD,and the experiment and clinical research with single herb,compounds and patent formula,and thus to help in better understanding of NAFLD and contributing the prevention and treatment of the disease.