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HPV致宫颈癌分子机理研究 被引量:5

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摘要 宫颈癌是仅次于乳腺癌而引起妇女癌症相关死亡的重要原因 ,目前认为人乳头瘤病毒(HPV)是宫颈癌的主要致病因子。该文对HPV基因组特征与宫颈癌的易感性 ,宿主感染后HPV影响机体组织人白细胞抗原 (HLA)分子表达 ,逃脱免疫监视 ,降解 p5 3,使 pRb失活 ,下调抑癌基因p2 1、p2
作者 韩苏夏
出处 《国外医学(妇幼保健分册)》 2003年第1期20-22,共3页 Foreign Medical Sciences (Section of Maternal and Child Health)
基金 陕西省科技研究发展计划项目资助 (No .2 0 0 0k14 G13)
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