乳腺癌患者血清癌抗原15-3癌胚抗原检测的临床意义

Clinical Significance of Serum CA15-3 and CEA in Patients with Breast Cancer

目的 :探讨癌抗原 15 3 (CA15 3 )和癌胚抗原 (CEA)对乳腺癌的临床意义。方法 :对 3 5 8例乳腺癌患者血清CA15 3和CEA的测定结果进行分析。结果 :未转移、复发乳腺癌患者血清CA15 3和CEA的阳性率较低 ,手术后CA15 3和CEA值较手术前下降 ,有转移、复发乳腺癌患者血清CA15 3和CEA的阳性率增高。结论 :血清CA15 3和CEA对乳腺癌转移、复发有诊断意义。

Objective:To investigate the clinical value of CA15 3 and CEA in patients with breast cancer.Methods:Serum levels of CA15 3 and CEA in 358 patients with breast cancer were reviewed.Results:The positive rates of CA15 3 and CEA were lower in patients without metastatic and recurred breast cancer but increased in those with metastatic and recurred breast cancer. Serum levels of CA15 3 and CEA decreased after modified radical mastectomy.Conclusion:CA15 3 and CEA are of clinical value in diagnosis of metastasis and recurrence of breast cancer.