降逆汤加减治疗鼻咽癌放疗所致胃肠副反应的研究

Study of Jiang Ni Tang on gastrointestinal reaction during radiotherapy of nasopharyngeal carcinoma

目的 观察降逆汤加减治疗鼻咽癌患者放疗中出现的恶心、呕吐等胃肠反应的疗效 ,探讨其治疗价值。方法 将 86例经病理检查确诊为鼻咽癌 ,并接受全剂量外照射 ,放疗中出现较明显的胃肠反应的患者随机分成治疗组 (放疗 +降逆汤加减治疗 )和对照组 (放疗 +胃复安治疗 )。结果 治疗组痊愈 2 0例 (47.6 % ) ,显效 10例 (2 3.8% ) ,有效 8例 (19.1% ) ,无效4例 (9.5 % ) ,总有效率为 90 .5 % ;对照组痊愈 8例 (18.2 % ) ,显效 12例 (2 7.3% ) ,有效 14例(31.8% ) ,无效 10例 (2 2 .7% ) ,总有效率为 73.3%。两组比较差异显著。结论 降逆汤加减治疗鼻咽癌放疗所致的恶心、呕吐等胃肠副反应疗效显著 。

Objective It is to evaluate the therapeutic value of Jiang Ni Tang by observing its effect on gastrointestinal reaction during radiotherapy of nasopharyngeal carcinoma. Methods 86 patients with nasopharyngeal carcinoma were randomized into treatment group and control group. All accepted total external doses of radiotherapy and the treatment group were treated with Jiang Ni Tang while the control group treated with metoclopramide. Results The total effective rat of the treatment group was 90.5% and that of the control group was 73.3%. There was significant difference between two groups. Conclusion Jiang Ni Tang is effective and safe on gastrointestinal reaction during radiotherapy of nasopharyngeal carcinoma.