MHC基因结构及其功能的研究进展

Research Progress of MHC Gene and Its Function

主要组织相容性复合体(Major Histocompatibility Complex,MHC)是脊椎动物体内与免疫功能密切相关的一类庞大的基因家族,在调节免疫系统识别自身和异物之间起着重要的作用。最近对其在动物体内遗传进化等方面进行了广泛的研究,本文从鱼类、两栖类、鸟类和哺乳类几个方面分别介绍MHC基因的研究进展。本文从MHC基因的结构、检测方法、功能等方面进行了相关的阐述。

Major Histocompatibility Complex (M HC) gene is closely related to the immune function of a large gene families ,it plays an important role in regulating the immune system to identify themselves and between foreign body .This article ,respectively ,carried out a detailed elaboration from the progress of its structure ,mechanism ,testing and functional aspects .