重复经颅磁刺激对脑梗死患者运动功能恢复的影响

Influence of transcranial magnetic stimulation on the recovery of motor dysfunction following cerebral infarction

目的观察重复经颅磁刺激(rTMS)对脑梗死患者运动功能恢复的影响。方法共选取60例脑梗死偏瘫的患者,随机分为低频刺激组,高频刺激组,对照组,每组20例。患者均接受脑梗死常规治疗,低频组和高频组在常规治疗基础上予以每天30 min的rTMS治疗,疗程10 d。比较治疗前后患者的运动功能,采用简式Fugl-Meyer评分(FMA)评定,同时检测各组脑梗死患侧运动诱发电位(MEP)潜伏期、波幅。结果治疗后,三组FMA评分均有明显的提高(P<0.05),低频组及高频组FMA评分明显高于对照组(P<0.05),低频刺激组和高频刺激组相比,FMA评分差异无统计学意义(P>0.05),但低频刺激组MEP潜伏期较高频刺激组缩短(P<0.05)、波幅峰值高于高频刺激组(P<0.05)。结论低频及高频刺激均有利于脑梗死患者运动功能的康复。

Objective To observe repetitive transcranial magnetic stimulation ( rTMS) for the recovery of motor dysfunction in patients with cerebral infarction .Methods Sixty cerebral infraction patients with hemiplegia were enrolled and randomly divided into low-frequency stimulation group ,high-frequency stimulation group and control group with twenty cases in each group .All patients received conventional treatment for cerebral infarction .Both low&nbsp;and high-frequency groups also received thirty minutes of daily rTMS treatment for ten consecutive days .Simplified Fugl-Meyer score (FMA) and latency and amplitude of motor evoked potential (MEP) were compared before and af-ter treatment.Results After treatment,FMA score among 3 groups significantly improved(P<0.05),higher in both low and high-frequency groups compared with the control group (P<0.05),although the score had no significant difference in both low and high-frequency groups(P>0.05),MEP latency was shorter(P<0.05) and amplitude higher(P<0.05) in the low-frequency group than the high-frequency group.Conclusion Low and high-frequency stimulation is beneficial for the recovery of motor function in patients with cerebral infarction .