益生菌未必是改善成人健康的助力剂

Probiotics are not necessarily a booster for improving adult health

益生菌是指能够给宿主带来健康益处的"活微生物",是临床上应用最广泛的肠道微生态制剂。近年来,大量研究表明益生菌在调节肠道微生物、控制体质量、改善胰岛素抵抗、降压、降脂等方面均有益处。本文总结了益生菌对成人肠道微生物、胃肠道健康、心血管疾病风险因素、免疫反应、女性泌尿生殖系健康和心理健康的影响,阐述益生菌与成人健康的关联:益生菌不能在肠道微生物群中引起持续变化,对特定人群和潜在病态人群补充益生菌可能更有效,而对健康成年人补充益生菌的益处及可行性仍不确定。我们需要对益生菌的使用进行更多的研究,以获得更有力的证据来证实益生菌对健康成人带来的健康益处,从而指导益生菌的合理使用。

Probiotics are ' living microorganisms' that can bring health benefits to the host and are the most widely used intestinal microecological preparations. In recent years,a large number of studies have shown that probiotics are beneficial in regulating gut microbiota,controlling weight,improving insulin resistance,lowering blood pressure and lowering lipids. This review summarizes the influence of probiotics to gut microbiota,intestinal health,cardiovascular disease risk factors,immune response,female urogenital system health and mental health in healthy adults,and then explain the associations between probiotics and adult health. Probiotics can not cause continuous changes in gut microbiota and may be more effective for specific populations and potentially sick populations,while the benefits and feasibility of probiotics supplementation for healthy adults remain uncertain. More researches on the use of probiotics are needed to obtain stronger evidence of the health benefits of probiotics in healthy adults in order to guide the rational use of probiotics.