摘要
皮肤鳞状细胞癌是一种发病率较高的恶性肿瘤,病情发展快,破坏性大,可发生多处转移,严重威胁着人类的生命健康。在临床治疗肿瘤过程中,手术、放化疗等基本手段显现出明显的不良反应和局限性,近年来中药以其安全性高、不良反应小等抗肿瘤作用日益受到医学界重视。随着对中药研究的深入,从中药中提取分离的有效单体在生物活性方面表现出多种抗肿瘤作用。该篇综述总结了当前中药单体对皮肤鳞状细胞癌的研究进展,旨在为临床应用和深入研究提供参考。
Cutaneous squamous cell carcinoma is a malignant skin tumor with a high incidence.This destructive disease has the characteristics of rapid development and multiple metastases,threatening human life and health.Basic methods such as surgery,radiotherapy and chemotherapy show obvious side effects and limitations in the process of clinical oncotherapy.The anti-tumor effect of traditional Chinese medicine due to its high safety and small side effects have been paid more attention in the medical community.With the deepening research of traditional Chinese medicine,traditional Chinese medicine monomer as an active ingredient extracted from traditional Chinese medicine has multiple anti-tumor effects in biological activity.This review summarizes the current research progress of traditional Chinese medicine monomers on cutaneous squamous cell carcinoma,aiming at providing a reference for clinical application and in-depth research.
作者
张荔
刘杰
陈群
燕秋
刘基巍
ZHANG Li;LIU Jie;CHEN Qun;YAN Qiu;LIU Jiwei(Dalian Medical University,Dalian 116044,Liaoning,China;Longhua Hosptial,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;First Affiliated Hospital of Dalian Medical University,Dalian 116011,Liaoning,China)
出处
《辽宁中医药大学学报》
CAS
2019年第9期126-129,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(81572881)
关键词
皮肤鳞状细胞癌
中药单体
姜黄素
黄芩素
白藜芦醇
cutaneous squamous cell carcinoma
monomers from herbal medicine
curcumin
baicalensis
resveratrol