阻塞性睡眠呼吸暂停综合征心血管相关生物标志物研究进展

Research progress in cardiovascular related biomarkers in obstructive sleep apnea syndrome

阻塞性睡眠呼吸暂停综合征是临床常见病,以间歇性缺氧、二氧化碳潴留、反复微觉醒及睡眠结构紊乱为主要特征,已被证实是心血管疾病的独立危险因素。目前的研究旨在通过生物标志物从阻塞性睡眠呼吸暂停综合征患者中筛选出心血管疾病高危患者,从而尽早予以预防和治疗。

Obstructive sleep apnea syndrome is a common clinical disease characterized by intermittent hypoxia,carbon dioxide retention,recurrent micro-awakenings and sleep structure disorders,which has also been proved to be an independent risk factor for cardiovascular disease.Current researches have aimed at screening high-risk cardiovascular disease patients from obstructive sleep apnea syndrome patients using biomarkers so as to treat them early.Here,we reviewed recent studies that were focused on cardiovascular disease related biomarkers in obstructive sleep apnea syndrome.