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门冬氨酸钾镁对不稳定型心绞痛患者左心室功能的影响

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摘要 目的观察门冬氨酸钾镁治疗不稳定型心绞痛的临床疗效和对左心室功能的影响。方法将 72例不稳定型心绞痛患者随机分为 2组。在常规治疗基础上 ,治疗组 (36例 )加用门冬氨酸钾镁静注 ,对照组 (36例 )不用门冬氨酸钾镁 ,对比两组患者治疗前后心绞痛症状及心电图变化 ,并应用彩色多普勒超声心动图观察左心室功能变化。结果两组症状缓解率相似 (80 .6 %与 77.8% ,P >0 .0 5 ) ,心电图有效率治疗组高于对照组 (76 .4 %与 39.1% ,P <0 .0 5 ) ,两组治疗前后左室收缩功能参数均在正常范围 ,舒张功能参数异常 ,治疗后均有改善 ,EPFV增加 ,APFV下降 ,E/A从治疗前 <1转为治疗后 >1,且治疗组改善程度明显高于对照组 (P <0 .0 1)。结论用门冬氨酸钾镁静注治疗不稳定型心绞痛 ,对左心室舒张功能改善明显 ,可作为安全有效的辅助治疗药物。
作者 徐亚平 董玲
出处 《中国综合临床》 北大核心 2003年第5期413-414,共2页 Clinical Medicine of China
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