青年人胃癌43例临床分析

The clinical analysis of gastric carcinoma in 43 young cases

目的分析青年人胃癌的临床特点。方法对我院 1991年 1月～ 1999年 8月 4 3例有完整临床病理资料的 4 0岁以下及同期 6 2 6例 4 0岁以上胃癌患者进行了对比分析。结果青年组女性多于男性 (1.2 6∶1) ,临床病理分析肉眼分型早期 2例 ;进展期BorrmannⅠ型 8例 (19% ) ,Ⅱ型 2 1例 (4 9% ) ,Ⅲ型 8例 (19% ) ,Ⅳ型 4例 (9% )。组织分型以低分化腺癌及印戒细胞癌多见 (分别占 4 4 %和 4 0 % )。TNM分期以Ⅰ期及Ⅳ期多见 (分别为 4 0 %和 30 % )。手术患者 36例(84 % ) ,其中根治性切除 2 5例 (5 8% )。结论青年人胃癌女性多于男性 ;病理类型以低分化腺癌和印戒细胞癌为多 ;根治性切除的机会低于中老年人 ;根治性切除术后的 3年和 5年的生存率低于中老年人。

Objective To investigate the clinical characters in young gastric carcinoma cases. Methods 43 patients who had completed clinicopathological data, aged below 40 years old, and 626 patients aged above 40 years old with gastric carcinoma were analyzed retrospectively in our hospital from Jan 1991 to Aug 1999. Results The ratio of male to female was 1:1.26. According to clinical pathology,2 cases were at early stage by macroscopic classification.Advanced type was the main classification, including 8 Borrmann I cases(19%), 21 Borrmann II cases(49%), 8 Borrmann III cases(19%) and 4 Borrmann IV cases(9%). Poorly differentiated adenocarcinoma and ring cell carcinoma were the dominant pathological type(accounting for 44% and 40%, respectively). Stage I and stage IV were found about 40% and 30% in TNM classification.The radical resection cases were 25 cases(58%) in 36 cases(84%)treated with operation. Conclusion The gastric cancer in young cases is more in female than in male. Poorly differentiated adenocarcinoma and ring cell carcinoma are the dominant pathological type. The ratio of radical resection in young is lower than that in elderly. After radical resection, 3-year and 5-year survival rate of the young is lower than that of the elderly.