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异种胰岛移植治疗糖尿病研究若干进展

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摘要 采用免疫隔离、免疫抑制等方法可使移植物长期存活。免疫隔离多使用微包囊和大包囊技术,使移植物免遭受体的排斥。移植的部位不仅要考虑免疫豁免的问题,也要考虑局部是否缺血缺氧的问题。获得大量高纯度的胰岛是移植成功的前提,也是异种移植的优势。异种胰岛移植排斥的关键原因是细胞免疫,CD4^+细胞起着最重要的作用。关于逆转录病毒感染是否会造成不良后果,目前仍存在争议。
作者 胡吉
出处 《国外医学(内分泌学分册)》 2003年第B04期1-3,共3页 Foreign Medical Sciences(Section of Endocrinology)
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