小剂量尿激酶治疗老年超时间窗脑梗死疗效分析

THROMBOLYTIC THERAPY FOR CEREBRAL INFARACTION WITH LOW-DOSE UROKINASE IN BROADENED THERAPEUTIC WINDOW

目的 :探讨小剂量尿激酶对老年超时间窗急性脑梗死治疗的疗效。方法 :对照组采用静脉滴注低分子右旋糖酐、复方丹参注射液、胞二磷胆碱等常规方案 ,治疗组采用在与对照组相同的治疗方案的基础上加用静脉滴注小剂量尿激酶 ,进行疗效对比观察。结果 :治疗组总有效率 93.8% ,对照组总有效率 78.8% ,两组间总有效率有显著性差异 (P <0 .0 5 )。结论 :小剂量尿激酶超时间窗治疗老年急性脑梗死疗效较好。

Objective:To observe the clinical curative effect of the acute cerebral infaraction which were using intravenous thrombolytictherapy with low-dose urokinase. Methods: Using intravenous drip with low molecular dextran cytidine diphosphate choline, compound injection of tanshinore in control group.Given a low-dose urokinase on the base of routine scheme.Curative effect were compared between two groups . Results: The total effective rate of therapteutic group were 93.8% and that of control group were 78.8%. A remarkable difference was noticed between them(P<0.05). Conclusion: Thrombolytic therapy for acute cerebral infarction with low-dose urokinase in broadened therapeutic windowis is beneficial and safe.