由芳基炔基硒醚与对甲苯磺酸反应制备芳基硒代羧酸酯

Synthesis of Aryl Selenoesters by Reaction of Alkynyl Aryl Selenide and p-Toluenesulfonic Acid

端炔、二醋酸碘苯和二芳基二硒醚于二氯甲烷溶剂中制得芳基炔基硒醚,再将芳基炔基硒醚和对甲苯磺酸在二氯甲烷中加热回馏,冷却后加入适量水即可一锅法制得芳基硒代羧酸酯.该法具有原料易得、反应条件温和、操作方便和产率较高(70%～81%)等优点.

Alkynyl aryl selenides were prepared from the reaction of terminal alkynes with iodobenzene diacetate and diaryl selenides in methylene chloride at 0 ℃.A mixture of the alkynyl aryl selenide and p-toluenesulfonic acid in methylene chloride was refluxed for 4 h,cooled, and then treated with water to afford aryl selenoesters. This one-pot synthetic procedure of aryl selenoester has the advantage of ready availability of starting materials, mild reaction condition, convenient manipulation and good yields (70%～81%).