国产和进口乌拉地尔治疗高血压的费用-效果分析

Cost-effectiveness analysis of domestic and imported urapidil in treat ment of patients with hypertention

目的 :比较国产乌拉地尔 (利喜定 )与进口乌拉地尔 (压宁定 )治疗外科手术时高血压的效益。方法 :根据文献选择 60例重症高血压病人 ,将他们随机分为两组 :国产乌拉地尔组 (n =3 0 ) ,进口乌拉地尔组 (n=3 0 ) ,应用药物经济学的费用 效果分析方法进行评价。结果 :国产乌拉地尔用药后SBP平均下降 42 .70mmHg,降幅 2 3 % ;进口乌拉地尔用药后SBP平均下降 3 9.85mmHg,降幅 2 2 %。DBP两组下降分别为 :国产乌拉地尔 2 6.90mmHg(2 5 % ) ,进口乌拉地尔 2 6.70mmHg(2 5 % )。治疗前后两组差别均无显著性 (P >0 .0 5 )。但进口乌拉地尔价格较贵。结论 :通过药物经济学的分析 。

AIM: To explore the cost-effectiveness analysis of domestic and imported urapidil in t reatment of patients with hypertention. METHODS: 60 cases of sev ere hypertention were divided into two groups randomly: domestic urapidil (n=30) and imported urapidil group (n=30). The data we re evaluated with cost-effectiveness analysis. RESULTS: Domesti c and imported urapidil showed the same effectiveness in treatment of severe hyp ertention. CONCLUSION: Domestic urapidil is better than imported based on the cost-effectiveness analysis.