肝动脉栓塞治疗肝海绵状血管瘤的疗效评价(附21例报告)

Hepatic Arterial Embolization in the Treatment of Cavernous Hemangioma of the Liver: Report of 21 Cases

目的 :评价平阳霉素碘化油乳剂 (PLE)与无水乙醇 碘化油乳剂 (ELE)经肝动脉栓塞治疗肝海绵状血管瘤 (CHL)的疗效并进行比较。材料和方法 :回顾性分析经肝动脉栓塞治疗 2 1例肝脏海绵状血管瘤 ,15例肝动脉注入PLE ,6例肝动脉注入ELE ,观察其栓塞前后肿瘤大小变化、临床症状的缓解和并发症发生情况。结果 :PLE与ELE栓塞后肝海绵状血管瘤均有明显缩小 ,临床症状缓解 ,术后 6个月随访观察 ,肿瘤最大直径分别由术前 7.5 7± 3 .91cm、7.5 0± 1.5 9cm缩小为 4.3 3± 0 .80cm、3 .72± 0 .45cm ,有显著性差异 (P <0 .0 5 ) ,但PLE栓塞术后并发症明显较ELE要轻。结论 :介入栓塞治疗CHL疗效肯定 ,PLE肝动脉栓塞治疗CHL的安全性优于ELE。

Purpose: To investigate and compare the therapeutic efficacy of pingyangmycin lipiodol emulsion (PLE) and ethanol lipiodol emulsion (ELE) in the treatment of cavernous hemangioma of the liver. Materals and Methods: Transarterial embolization using PLE or ELE were done in 15 cases or 6 cases respectively. The size of tumor were measured pre and post embolization. The clinical symptoms and complications were also evaluated. Results: The tumor size reduced significantly after PLE or ELE embolization;the maximal tumor diameter were (7.57±3.91)cm and (7.50±1.59)cm respectively before embolization,but in follow up of six months,the size of tumor reduced to(4.33±0.80)cm and (3.72±0.45)cm which were treated by PLE and ELE respectively (P<0.05). The clinical symptoms were control significantly too. Compared with ELE,less complications occurred in the treatment of PLE. Conclusion: It is an effective methed for treating CHL by trasarterial embolization,and PLE is superior to ELE while considering their effectiveness and safety.