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异丙酚-芬太尼复合麻醉用于人工流产术的效果观察 被引量:1

Observation of the clinical effects of propofol in combination with fentanyl anesthesia for abortion
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摘要 目的 观察比较异丙酚 芬太尼、异丙酚在人工流产术中的麻醉效果。方法  6 0例ASAⅠ~Ⅱ级、年龄 2 0~ 4 1岁、全身麻醉下行人工流产术者 ,随机分为两组 ,每组各 30例。A组为异丙酚 芬太尼组 ,B组为异丙酚组。A组以芬太尼 1μg·kg-1和异丙酚麻醉诱导。B组仅以异丙酚麻醉诱导 ,术中两组均以异丙酚静脉维持 ,术中持续监测HR、SBP、DBP、SPO2 、BIS。结果 (1)在达到同等麻醉深度时 ,A组的麻醉诱导剂量、静脉维持速率、麻醉苏醒时间各指标明显低于B组 (P <0 0 1) ;(2 )A组诱导后、手术结束时的HR、SBP、DBP、SPO2 与诱导前各指标相比均无明显差异 (P >0 0 5 ) ;B组诱导后指标与诱导前相比差异有显著性 (P <0 0 1) ,手术结束时上述指标与诱导前相比差异有显著性 (P <0 0 5 )。B组SPO2 诱导后与诱导前相比有非常显著的差异 (P <0 0 1) ,手术结束时SPO2 与诱导前相比差异有显著性 (P <0 0 5 )。 (3)两组病人手术中知晓率均为 0。B组有 16 7%病人主诉注射部位疼痛 ,6 7%病人在术后主诉腹部疼痛。AB两组的手术满意率为 10 0 %。结论 异丙酚 芬太尼用于人工流产术剂量小、血流动力学平稳、苏醒快、副作用少而成为理想的麻醉选择。 AIM A comparison of the clinical effects between propofol with fentanyl and propofol for abortion. METHODS Sixty ASA Ⅰ~Ⅱ patients scheduled for abortion under going general anesthesia were enrolled in this study. Age ranged from 20 to 41 years old. They were randomly divided into two groups with 30 cases in each, which are group A: propofol with fentanyl intravenous anesthesia and group B: propofol anesthesia. The anesthesia was induced by either propofol with a dose of 1 μg·kg -1 fentanyl in group A or propofol in group B. The anesthesia was maintained by a continuous propofol infusion. The ECG, SBP, DBP, SPO 2 and BIS were monitored peri operatively. RESULTS (1)At the same depth of anesthesia, the dose of induction and the rate of intravenous infusion in group A were much lower than those of group B. The time to awaking in group A was more rapid than that of group B. (2) There were no significant changes in HR, SBP, DBP and SPO 2 in group A during and after operation ( P> 0 05). However, there were significant changes in HR, SBP, DBP from the beginning of induction to during anesthesia ( P< 0 05) and the end of operation ( P< 0 01) in group B. There was a significant decrease in SPO 2 from the beginning of iduction to during anesthesia ( P< 0 01) and the end of the operation ( P< 0 05). (3) Percentage of intra operative awareness or recall was 0 in two groups. There were 16 7% patients who felt pain on injection and there were 6 7% patients who felt pain in the low abdominal in group B. Percentage of satisfaction was 100% in each of two groups. CONCLUSION Propofol in combination with fentanyl anesthesia has a much low dose of induction and maintenance of propofol, intra operative hemodynamic stability, a more rapid emergence from anesthesia, and a much low incidence of side efforts, which compare with propofol anesthesia. It is ideal anesthesia for abortion.
出处 《安徽医药》 CAS 2003年第1期19-21,共3页 Anhui Medical and Pharmaceutical Journal
关键词 异丙酚—芬太尼 复合麻醉 人工流产术 效果观察 propofol with fentanyl balanced anesthesia abortion
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