哌氟合剂治疗硬膜外阻滞后寒战效果观察

Treatment of shivering during epidural anesthesia by Meperidine-Droperidol

目的 :探讨硬膜外阻滞后寒战的治疗方法。方法 :对 96例硬膜外阻滞后出现寒战的患者随机分成 3组 ,分别经莫非氏滴管静脉滴入哌替啶 5 0mg、哌替啶 5 0mg +氟哌啶醇 2 5mg(以下简称哌氟合剂 )、芬太尼 0 0 5mg+氟哌啶醇 2 5mg(即氟芬合剂 1 2剂 ) ,观察这 3组治疗寒战结果及其副反应进行比较。结果 :3组治疗寒战的有效率分别为 97%、10 0 %、5 6% ,氟芬合剂组寒战缓解 15分钟后一部分患者再出现寒战其复发率为 2 8% ,其余两组患者寒战缓解持续 1小时以上 ,无出现复发现象。哌替啶组恶心、呕吐发生率为 4 1% ,其余两组无出现恶心、呕吐的副反应。哌替啶组有 1例患者和哌氟合剂组有 2例患者用药后出现轻度呼吸抑制 ,经面罩吸氧后 ,血氧饱和度恢复正常 ,其余患者用药前后呼吸无明显变化。结论 :哌氟合剂能有效治疗硬膜外阻滞后的寒战反应 ,且其副作用发生率低 ,寒战复发少。

Objective:To study the treatment methods of shivering during epidural anesthesia.Methods:96 patients with shivering in epidural anesthesia were randomly divided into three groups.These patients were received intravenous drip administration of Meperidine(50mg),Meperidine Droperidol mixture(M D M)(Meperidine 50mg and Droperidol 2 5mg),Droperidol Fentanyl mixture(D F M)(half of one dose) respectively.The therapeutic results to shivering and side reactions were compared.Results:The effective rates of treating shivering in three groups were 97%,100% and 56% respectively.The shivering recurred in some patients of D F M group 15 min after relief,and its recurrence rate was 28%.The other groups had no recurrence of shivering over 1h after relief.The incidence of side reaction,nausea and vomiting,was 41% in Demerol group,and naught in other groups.A patient in Meperidine group and two patients in M D M group had light respiration inhibition,and their SpO 2 were recovered after O 2 inhalation through mask.The other patients had no significant changes in respiration pre and post administration.Conclusion:M D M can cure shivering during epidural anesthesia,and has less incidence of side reaction and less recurrence rate of shivering.