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Ⅱ型糖尿病患者血清中超氧化物歧化酶含量变化的临床实验观察 被引量:4

Clinical and experimental observation on the change of SOD contant in serum of patientswith non insulin dependent diabetes mellitus
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摘要 目的 :探讨超氧化物歧化酶 (SOD)在Ⅱ型糖尿病 (NIDDM)患者血清中的变化。方法 :采用黄嘌呤氧化酶法测定血清中SOD的水平。结果 :(1)NIDDM组血清总SOD(TSOD)与对照组比较含量无明显差别 (P >0 0 5 ) ,MnSOD及CuZnSOD与对照组比较分别高于和低于正常对照组 (P <0 0 1)。 (2 )男女二组的性别比较差异无显著性 (P >0 0 5 )。结论 :检测血清中SOD对预测NIDDM患者血管并发症的发生。 Objective:To evaluate the change of superoxide dismutase(SOD) in patients with non insulin dependent diabetes millitus(NIDDM).Methods:SOD content in serum was determined with xanthine oxidase.Results:1.There was not significant difference in serum levels of total SOD(TSOD) between NIDDM group and control group(P>0 05).However,Mn SOD in NIDDM group were higher than that in control group,and CuZn SOD in NIDDM group were lower than that in control group,respectively(P<0 01).2.There was not significant difference between male and female.Conclusions:To determine the SOD content in serum of patients with NIDDM has great significance for predicting occurrence and development of complication as vascular disease.
作者 唐国全
出处 《广西医学》 CAS 2003年第5期687-688,共2页 Guangxi Medical Journal
关键词 Ⅱ型糖尿病 血液检验 超氧化物歧化酶 黄嘌呤氧化酶法 Non insulin dependent diabetes mellitus Superoxide dismutase
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  • 1[1]Machata E, Shimamura H, Kiyose H, et al. Relationship smong glycated comouds, SOl) activity, snd other related analytes in diabetic patients elassified by ages. Nippon Ronen lgakkai Zasshi 1991 ;28(4) :520

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