血管性帕金森综合征临床与影像学分析(附43例报告)

Analysis of the clinical manifestations and the imaging changes in 43 patients with vascular parkinsonism

目的 :探讨血管性帕金森综合征 (VP)的临床与影像学特点。方法 :对 4 3例VP患者的临床表现及影像学结果进行回顾性分析。结果 :本组绝大多数患者有高血压病、动脉硬化及卒中史。临床表现以肌强直———少动为主 ,静止性震颤相对少见 ,常伴有智能障碍、假性球麻痹、尿失禁等。影像学改变以基底节区、脑室周围多发腔隙性梗死为主 ,常伴脑萎缩、白质疏松。结论 :VP的临床表现以肌强直———少动为主 ,静止性震颤少见 ;影像学改变主要为基底节区。

Objective:To explore the clinical features and the imaging changes in vascular parkinsonism(VP).Methods:Clinical manifestations and imaging changes were retrospectively investigated in 43 patients with VP.Results:Most of the patients had the history with hypertension,arteriosclerosis or stroke.The patients with VP were more likely to present bradykinesia rigidity rather than rest tremor.In addition,they were more likely to accompany dementia,medullaparalysis,urinary incontinence.Imaging changes mainly displayed multiple lacunar infarcts in basal ganglia and periventrical cerebral white matter,and frequently accompanying with cerebral atrophy or leucoaraiosis.Conclusions:The clinical manifestations in VP are more likely to present bradykinesia rigidity rather than rest tremor.And multiple lacunar infarcts in basal ganglia and periventrical cerebral white matter plays an important role in imaging changes.