古蔺雪胆中的新三萜皂苷(英文)

New Triterpenoid Glycosides from Hemsleya penxianensis var. gulinensis

从采自四川汉源县的古蔺雪胆 (Hemsleyapenxianensisvar.gulinensis)中分到 9个三萜皂苷化合物 ,通过化学反应和光谱方法鉴定了它们的结构。其中 7个为已知化合物 ,分别为齐墩果酸 2 8 O β D 吡喃葡萄糖苷 (1) ,3 O β D 吡喃葡萄糖醛基齐墩果酸苷 (3) ,3 O β D 吡喃葡萄糖醛基 -齐墩果酸 2 8 O α L 吡喃阿拉伯糖苷 (4 ) ,3 O β D 吡喃葡萄糖醛基 -齐墩果酸 2 8 O β D 吡喃葡萄糖苷 (5 ) ,3 O α L 阿拉伯糖基 (1→ 3) β D 吡喃葡萄糖醛基 -齐墩果酸 2 8 O β D 吡喃葡萄糖苷 (6 ) ,3 O (6′ 丁酯 ) β D 吡喃葡萄糖醛基 -齐墩果酸 2 8 O α L 阿拉伯糖苷 (7) ,3 O (6′ 丁酯 ) β D 吡喃葡萄糖醛基 -齐墩果酸 2 8 O β D 吡喃葡萄糖苷 (8)。两个新化合物 ,即雪胆皂苷A (2 )和雪胆皂苷B (9)。

Two new triterpenoid saponins were isolated from t he roots of Hemsleya penxianensis var. gulinensis together with seven know n saponins oleanolic acid 28-O-β-D-glucopyranoside ( 1 STBZ ), ole anolic acid 3-O-β-D-glucuropyranoside ( 3 STBZ ), 3-O-β-D-glu curopyranosyl-oleanolic acid-28-O-α-L-arabinopyranoside ( 4 STBZ ),3-O-β-D-glucuropyranosyl-oleanolic acid-28-O-β-D-glucuropyranosi de ( 5 STBZ ),3-O-α-L-arabinopyranosyl-(1→3 BF )- BFQ β-D -glucuropyranosyl-oleanolic acid-28-O-β-D-glucopyranoside ( 6 ST BZ ),3-O BF -( BFQ 6′-butyl ester BF )- BFQ β-D-glucuropyran-o syl-oleanolic acid-28-O-α-L-arabinopyranoside ( 7 STBZ ),3-O BF -( BFQ 6′-butyl ester BF )- BFQ β-D-glucuropyranosyl-oleanolic acid-28-O-β-D-glucopyranoside ( 8 STBZ ).The structures of deter mined as:oleanolic acid 28-O-β-D-glucopyransyl BF -( BFQ 1→6 BF )- BFQ β-D-glucopyranoside ( 2 STBZ ),3-O-α-L-arabonipyranosyl BF -( BFQ 1→3 BF )-( BFQ 6′-butyl ester BF )- BFQ β-D-gluc uropyranosyl-oleanolic acid-28-O-β-D-glucuropyranoside ( 9 STBZ ).Their structures were determined on the bases of the spectral and chemical e vidences.