期刊文献+

阿司匹林对人结肠腺癌细胞LS174-T凋亡及caspase-3活性的影响 被引量:2

Aspirin inhibited proliferation of human colon adenocarcinoma cell line LS174-T via induction of apoptosis independent of caspase-3 activation
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摘要 研究发现,长期服用阿司匹林可明显降低结肠肿瘤的发病率及预防致癌剂诱发结肠癌的发生[1]。本实验观察阿司匹林对人结肠腺癌细胞LS174-T凋亡及caspase-3活性的影响,以进一步探讨其作用机制。
出处 《第二军医大学学报》 CAS CSCD 北大核心 2003年第4期463-463,共1页 Academic Journal of Second Military Medical University
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参考文献5

  • 1Smalley WE,DuBois RN.Colorectal cancer and nonsteroidal anti-inflammatory drugs[].Advances in Pharmacology.1997
  • 2Eberhart CE,,Coffey R J,Radh ika A,et a.l Up-regu lation ofcyc looxygenase-2 gene expression in hum an colorectal ade-nom as and adenocarc inom as[].Gastroenterology.1994
  • 3Sheng H,ShaoJ,Kirkland SC,et al.Inhibition of human colon cancer cellgrowth by selective inhibition of cyclooxygenase-2[].The Journal of Clinical Investigation.1997
  • 4Vogt T,McClelland M,Jung B,et al.Progression and NSAID-induced apoptosis in malignant melanomas are independent of cyclooxygenase Ⅱ[].Melanoma Research.2001
  • 5Castano E,Dalmau M,Barragan M,et al.Aspirin induces cell death and caspase-dependent phosphatidylserine externalization in HT-29 human colon adenocarcinoma cells[].British Journal of Cancer.1999

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