多胺修饰β-环糊精的铜配合物对几种荧光染料的多点识别

Molecular recognition of several fluorescent dyes by copper(II) complexes with polyamine modified β-cyclodextrins

用荧光和紫外光谱滴定技术分别测定了 β-环糊精 ( 1 )、单 -[6-(乙二胺基 ) -6-脱氧 ]-β-环糊精 ( 2 )、单 -[6-(二乙烯三胺基 ) -6-脱氧 ]-β-环糊精 ( 3 )、单 -[6-(三乙烯四胺基 ) -6-脱氧 ]-β-环糊精 ( 4 )及其相应的铜配合物 ( 5、6、7)在 2 5℃时 ,p H=7.2的缓冲溶液中与几种染料分子形成超分子配合物的稳定常数。结果表明 ,与母体环糊精相比 ,铜键合修饰 β-环糊精可以增强主-客体间的静电相互作用 ,从而提高对一些底物的键合能力。从主 -客体间的尺寸 /形状适合关系讨论了主体 ( 1 -7)对染料分子识别机理。

The Spectrophotometric and spectrofluorometric titrations have been performed to give the stability constants for the supramolecular systems formed by β-cyclodextrin (1) , mono[6-(ethylenediamine)-6- dexoy]-β-cyclodextrin(2), mono [6 - (diethylenetriamino) - 6 - dexoy]-β -cyclodextrin(3), mono [6 - (triethylenetetraamino) - 6 - dexoy]- β- cyclodextrin (4) and their copper (II) complexes (5?6?7) with some dyes in phosphate buffer solution (pH 7.2, 0.1 mol·dm -3 ). As compared with parent β-cyclodextrin, the stability constants of the formed inclusion complexes by copper (II) complexes of polyamine modified β-cyclodextrins were found to be increased by electrostatic interaction. The molecular recognition mechanism is discussed from the viewpoint of the size/shape matching between guest molecular structures and host cavity.