2型糖尿病患者慢性并发症临床分析(附471例报告)

The retrospective analysis of chronic vascular complications of 471 Type 2 diabetic in patients

目的 分析 2型糖尿病住院患者各种糖尿病慢性并发症及相关大血管疾病的患病状况及相关危险因素。方法 以 4 71例 2型糖尿病住院患者为研究对象 ,依据患者的病历 ,针对各种糖尿病慢性并发症及相关大血管疾病进行统计分析。结果 入选患者中 ,糖尿病视网膜并发症者为 5 7.3 % ;糖尿病肾脏并发症者为 3 1.0 % ;糖尿病神经病变者为 5 6.5 % ;高血压为 5 0 .6% ;冠状动脉粥样硬化性心脏病为 2 6.9% ;脑血管疾病为 13 .6% ;下肢血管疾病为 5 .3 %。经多因素Logistic回归分析发现 ,患者的年龄、糖尿病病程、空腹血糖水平、收缩压水平、舒张压水平、甘油三酯水平分别为各种糖尿病慢性并发症及相关大血管疾病的独立危险因素。结论 为改善患者的预后 ,应重视对糖尿病高危人群的早期防治 ;对已出现 2型糖尿病的患者应采取降糖、降压、调脂等多种措施并重的综合治疗。

Objective To analyze the prevalence and risk factors of chronic vascular complications of type 2 diabetic in patients.Methods Data of the study came from 471 type 2 diabetic in patients from 1991 2000 in Peking Union Medical College Hospital (PUMCH).Results In the patients,57.3% have diabetic retinopathy;31.0% have diabetic nephropathy;56.5% have diabetic neuropathy;50.6% have hypertension;26.9% have coronary heart disease;13.6% have cerebrovascular disease;and 5.3% have vessel complication of lower limbs.Multivariate logistic regression analysis shows that age,duration of diabetes,fasting blood glucose,systolic blood pressure, diastolic blood pressure and triglyceride are the risk factors for chronic vascular complications,respectively.Conclusions In order to improve patient's prognosis, a multiple metabolic control in type 2 diabetic patients is urgently needed,which includes decreasing glycemia,reducing blood pressure and treating serum lipid disorders.