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TGF—β_1、PDGF—BB和糖尿病肾病 被引量：1

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摘要 转化生长因子β_1和血小板源性生长因子BB均为多功能细胞因子,糖尿病肾病时二者在肾脏局部的表达明显增强。转化生因子β和血小板源性生长因子BB均可使系膜区细胞外基质成分合成增多、降解减少,在肾小球、肾小管间质硬化中起重要作用。二者相互促进又相互制约,在糖尿病肾病发病机制中作用日益受到人们的重视。
作者 杜俊文
机构地区 河北医科大学第二医院内分泌科
出处 《国外医学（老年医学分册）》 2003年第3期118-120,共3页 Foreign Medical Sciences(Geriatrics)
关键词 糖尿病肾病 发病机制 转化生长因子Β1 血小板源性生长因子BB 细胞外基质
分类号 R587.2 [医药卫生—内分泌] R692 [医药卫生—泌尿科学]
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参考文献18

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国外医学（老年医学分册）
2003年 第3期

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