TGF—β_1、PDGF—BB和糖尿病肾病
被引量:1
摘要
转化生长因子β_1和血小板源性生长因子BB均为多功能细胞因子,糖尿病肾病时二者在肾脏局部的表达明显增强。转化生因子β和血小板源性生长因子BB均可使系膜区细胞外基质成分合成增多、降解减少,在肾小球、肾小管间质硬化中起重要作用。二者相互促进又相互制约,在糖尿病肾病发病机制中作用日益受到人们的重视。
出处
《国外医学(老年医学分册)》
2003年第3期118-120,共3页
Foreign Medical Sciences(Geriatrics)
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