中西医结合治疗贲门癌术后反流性食管炎

Combined Treatment of TCM and Western Medicine for Gastroesophageal Reflux after Operation of Cardiac Carcinoma

目的 探讨贲门癌切除术后反流性食管炎的治疗方法和疗效。 方法 应用单纯西药和中西医结合方法 ,分别治疗贲门癌切除术后胃食管反流的患者各 45例。并根据临床表现、X线食管钡剂造影检查、纤维胃镜检查对疗效进行判断。结果 中西医结合组症状有效率、食管钡剂造影检查好转率、纤维胃镜检查好转率分别为 93 3%、6 0 6 %、72 5 %,单纯西药治疗组为 75 6 %、2 5 8%、48 7%,两组间差异有显著性 (P <0 0 5 )。 结论 取半卧位睡眠、服用奥美拉唑、西沙必利能较为有效地控制胃食管反流 ,结合中医治疗更能提高治疗效果。

Objective To study combined treatment of TCM and western medicine for gastroesophageal reflux(GRE)after resection of cardiac carcinoma Methods Patients with postoperative GRE after resection of cardiac cancer were treated by single western medicine(Omeprazole and Cisapridi, n =45)or combination traditional Chinese and western medicine(western medicine add Jiaweiwendantang(加味温胆汤), n =45)respectively in random process.Results The effective rates of symptom,esophageal barium contrast radiography and fiber gastroscope examination in the single treatment group were 93.3%,60.6% and 72.5% respectively.And those in combination treatment group were 75.6%,25.8% and 48.7% respectively.The effect of the combination group was better than that of the control single group( P <0 05). Conclusion The gastroesophageal reflux exists in the majority of patients after resection of cardiac cancer.Sleep in semireclining position,omeprazole and cisapridi are the effective methods of treating GRE in postoperative cases.The combination therapy of GRE is more effective.