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地洛他定治疗慢性特发性荨麻疹的临床研究 被引量:5

Curative effect of desloratadine in the treatment of chronic idiopathic urticaria.
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摘要 目的 了解地洛他定治疗慢性特发性荨麻疹的疗效与安全性。方法 采用氯雷他定为对照药,对41例慢性特发性荨麻疹患者进行双盲随机临床试验,观察两药的临床疗效与不良反应。结果 地洛他定组有效率为85.7%,与氯雷他定组疗效(65.0%)相当,无严重不良反应。结论 地洛他定治疗慢性特发性荨麻疹具有疗效良好、安全性高的特点。 Objective To study the curative effects and safety of desloratadine in the treatment of chronic idiopathic urticaria. Methods Forty-one patients with chronic idiopathic urticaria were randomly divided into experimental group (desloratadine group) and control group (loratadine group) in a randomly double-blind controlled trial. The curative effects and adverse reactions were observed. Results After treatment the effective rate of desloratadtine and loratadine was 85.7% and 65.0% , respectively. There was no significant difference in curative effect between the two groups. No serious adverse effects were found. Conclusion Desloratadine is effective and safe in treating chronic idiopathic urticaria patiens.
作者 邹耘 陈兴平
出处 《华中医学杂志》 CAS 2003年第2期75-76,共2页 Central China Medical Journal
关键词 地洛他定 治疗 慢性 特发性荨麻疹 临床研究 Desloratadine Chronic idiopathic urticaria Curative effect
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参考文献2

  • 1[1]Geha RS, Meltazer EO. Desloratadine: A new, nonsedating, oral antihistamine. J Allergy Clin Immunol, 2001, 107(4):751
  • 2[2]Ring J, Hein R, Gauger A. Desloratadine in the treatment of chronic idiopathic urticaria. Allergy, 2001, 56:28

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