摘要
目的 评估甲苯胺蓝试剂盒Oratest诊断口腔粘膜病损的临床价值。方法 将 6 0例疑为癌或癌前病变的口腔粘膜病损患者随机分成两组 ,每组 30例。分别用Oratest试剂进行活体局部涂擦和含漱染色 ,观察其着色情况 ,并对照组织病理学诊断进行分析。结果 Oratest染色对口腔癌和上皮细胞异常增生诊断的灵敏度分别为93 9%和 4 2 9% ,而含漱法与局部涂擦法活体染色检测癌变的灵敏度无统计学差异 (P >0 1)。结论 Oratest活体染色可以应用于口腔癌的临床诊断 。
Objective\ The aim of the study was to evaluate the clinical efficacy of Oratest in detecting oral mucosal lesions.Methods\ Sixty patients with oral mucosal lesions that were suspected as carcinoma or premalignant lesions were divided into two groups randomly. The lesions were stained with Oratest by topical application in one group and rinse application in another group. Staining results were recorded and compared with the pathological diagnosis.Results\ The sensitivity of Oratest stain to oral carcinoma and dysplasia were 93 9% and 42 9%, respectively. The difference between rinse application and local application showed no significance(P>0 01).Conclusion\ Oratest can be used as a method of diagnosing squamous cell carcinoma of oral mucosa, but its reliability in screening oral pre_malignant lesions is still uncertain.\;
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2003年第2期124-126,共3页
West China Journal of Stomatology
基金
广东省科技计划资助项目 (编号 980 0 50 )
关键词
口腔癌
癌前病变
活体染色
甲苯胺蓝
oral cancer
\ pre_malignant lesions
\ stain in vivo
\ toluidine blue\