哈萨克族,维吾尔族同型半胱氨酸水平测定

Levels of plasma homocysteine in the Kazak nationality and the Uygur nationality

目的 测定哈、维、汉三个民族健康人和心脑血管病人血中同型半胱氨酸水平 ,探讨民族间的差别及同型半胱氨酸与传统危险因素的相关性。方法 选择三个民族健康人 10 8例 ,心脑血管病人 15 6例 ,测定血浆同型半胱氨酸水平 ,以及测定患者组传统的危险因素。对结果进行统计学处理。结果 1.三个民族健康人群同型半胱氨酸水平汉族高于哈族和维族。 2 .患者组血浆同型半胱氨酸水平均高于正常组 ,(除哈族男性、汉族女性患者组与正常组比较无显著性差异外 ,其余组均有显著性差异。) 3 .患者组同型半胱氨酸与传统危险因素相关性比较 ,除哈族的三酰甘油有相关性外 ,同型半胱氨酸水平与高胆固醇、高三酰甘油、高血糖、高血压、吸烟、饮酒无相关性。结论 同型半胱氨酸水平升高是三个民族心脑血管疾病的危险因素。 15 6例患者中 ,单纯同型半胱氨酸升高者 4.5 % ,合并一种以上危险因素的高同型半胱氨酸血症占患者总数的 42 .10 % 。

Object To defermin the levels of plasma homocystine in Kazak,Uygur and Han Nationality,and to analyse their related risk factors.Methods 156 cardio-cerebrovascular patients (Kazak 52,Uyqur52,Han 52) and 108 healthy (divided cases same as above) were chosen,their levels of plasma homocystine were measured,classical risk factors were also recorded and statisfically analysed. Results Plasma homocysteine levels in the healthy Ham nationality were higher than that of Kazak and Uygur nationality; Plasma homocysteine levels in patients were higher than that of control groups except that of Kazok male patients; Plasma homocysteine levels in patients of three nationalifies were not associated with classicat risk factors,except that of Kazak was associated with triglycerides.Conclusion Elevated homocysteine levels were a risk factor of cardio-cerebrovascular diseases,high homocysteine levels with classical risk factors easily resulted in and aggravated these diseases.