舌鳞状细胞癌区域淋巴结转移危险因素评估

Risk Factor Assessment for Lymph Node Regional Metastasis of Squamous Cell Carcinoma of Tongue

目的 探讨影响舌鳞癌淋巴结转移危险因素在预测颈淋巴结转移中的作用。方法 以 10 6例舌鳞癌患者原始资料为基础 ,取病灶最大直径、肿瘤细胞分化程度、浸润方式及组织学恶性度分级为危险因素进行统计学分析。结果 原发灶直径及肿瘤细胞分化程度与颈淋巴结转移无明显相关意义 ;而浸润方式及组织学恶性度分级与颈淋巴结转移有明显相关性。结论 舌鳞癌发生区域淋巴结转移的危险因素是浸润方式及组织学恶性度分级。

Objective\ The purpose of this study was to investigate the risk factors involving lymph node metastasis of squamous cell carcinoma and evaluate if the risk factors would be effective in predicting neck lymph node metastasis.Methods\ Based on the original data of 106 cases with carcinoma of tongue, four related factors, including maximal diameter, degree of differentiation, mode of invasion and histological grade of malignancy were analyzed statistically.Results\ The maximal diameter and the grade of tumor cell differentiation showed no significant correlation with cervical lymph node metastasis; but the mode of invasion and the histological grade of malignancy demonstrated a significant correlation.Conclusion\ The results obtained suggested that the mode of invasion and the histological grade of malignancy were closely related to cervical lymph node metastasis.\;