不同进食量对小鼠功能活动和生化指标的影响

Effect of food intake on functional activities and biochemical index in mice

目的 :探讨不同进食量在不同时间内对小鼠体重、记忆力、平衡耐力和相应生化指标的影响。方法 :预先计算小鼠每天平均进食量 ,按照 10 0 %食量 ,75 %食量、5 0 %食量、2 5 %食量及 0 %食量分为A、B、C、D、E组。实验过程中每 3d测试记忆力、平衡耐力和体重 1次 ,第 10d取血检测相应生化指标。结果 :实验第 3d ,E组体重、平衡耐力下降 ;实验第 6d和第 9d ,A组、B组、C组体重明显上升 ,A组、D组动物的记忆力低于B组和C组 ;实验第 10d ,D组血糖显著下降 ,总胆固醇及甘油三酯随进食量的减少而显著下降。结论 :适度减少进食量能维持正常体力和血糖水平 ,保持良好的记忆力 ,并有助于降低血中总胆固醇和甘油三酯。

AIM: To study the effect of food intake on weight, memory, staying balance and power, and some biochemical indexes in mice. METHODS: In accordance with the average food intake everyday, the animals were divided into five groups: group A took the average food intake fully, group B took 75% of the average food intake, group C took 50% of the average food intake, group D took 25% of the average food intake, and group E did not take any food at all. The weights, memory, staying balance and power were recorded every three days, the biochemical index was recorded on the 10th day. RESULTS: On the 3rd day, the weight and staying balance and power of mice in group E decreased. On the 6th and 9th day, the weight of mice in group ABC increased. Compared with group B and C, the memory group A and D decreased. On the 10th day, the blood glucose concentratoin in of group D decreased, total cholesterol and triglyceride also decreased with the reduction of food intake. CONCLUSION: A food intake of 75%-50% in all helpes to keep a good body status and memory, decreases total cholesterol and triglyceride in blood.