重型颅脑损伤合并下呼吸道感染与抗生素应用的相关性分析

Relations between clinical application of antibiotics and severe craniocerebral injury combined with lower respiratory tract infection

目的探讨重型颅脑损伤合并下呼吸道感染病例抗生素耐药性改变与抗生素应用的相关性。方法对某院129例重型颅脑损伤合并下呼吸道感染病例的抗生素耐药性改变与抗生素应用构成比的改变进行分析,找出二者之间的线性关系。结果重型颅脑损伤合并下呼吸道感染病例对抗生素耐药性的改变与抗生素应用构成比的改变有相关关系。结论抗生素应用构成比的改变可改变临床病原菌的耐药性。

Objective To study the relations between clinical application of antibiotics and severe craniocerebral injury combined with lower respiratory tract infection. Methods The change of antibiotic drug resistance in 129 patients with severe craniocerebral injury combined with lower respiratory tract infection and constituent ratio of clinical application of antibiotics were analysed. Results There was correlated relation between the change of antibiotic resistance in patients with severe craniocerebral injury combined with lower respiratory tract infection and that of constituent ratio of clinical application of antibiotics. Conclusion The change of constituent ratio of clinical application of antibiotics may alter the resistance of clinical pathogens.