实验动物瘙痒的评价

The Value of the Itch-associated Responses in Laboratory Animals

本文介绍了实验动物对痒刺激的各种反应 ,动物瘙痒反应可被类鸦片拮抗药物纳屈酮抑制。根据对动物受到痒刺激时所表现的行为和一系列的电生理活动进行分析 ,可客观地定量地评价动物瘙痒程度 ,利于抗瘙痒药物的药效作用和作用机制的研究。

The itch-associated responses of laboratory animals arisen from external stimulation were introduced in this article. The degrees of responses could be quantitatively evaluated by the analysis of skin nerve activities of laboratory animals and electrophysiologic parameters, which is useful for studying the effect of itch-resistant drugs.