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牵张致心室肌细胞电生理改变及其机制 被引量:5

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摘要 牵张心室肌细胞可致其电生理改变 ,具体表现为心室肌细胞生物电的改变及其兴奋性和传导性的变化 ,由此易促发室性心律失常。目前 ,此现象的确切机制仍然不是很明确 ,该现象可能和心室肌细胞在牵张过程中其牵张激活的离子通道被激活 ,心室肌细胞内与电活动有关的基因表达和蛋白合成增加 ,第 2信使的参与及心肌钙循环因素有关。关于此现象的确切机制还有待于进一步研究阐明。
出处 《起搏与心脏》 2003年第2期146-148,共3页
基金 国家自然科学基金资助项目 (批号 :30 2 70 5 5 9)
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参考文献15

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同被引文献45

  • 1尹军祥,程龙献.牵张引起心肌细胞内钙变化的研究进展[J].中国心脏起搏与心电生理杂志,2004,18(3):221-223. 被引量:1
  • 2杨蕙,伍卫,邓春玉,邓义军.心肌梗死后β_2肾上腺素受体对心室肌细胞钠钙交换电流的调控作用[J].中国心脏起搏与心电生理杂志,2006,20(5):427-430. 被引量:4
  • 3富路,曹君娴,谢荣盛.链霉素对心肌梗死大鼠离体心脏牵张时心律失常的影响[J].中国心脏起搏与心电生理杂志,2006,20(6):515-518. 被引量:1
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