云南省高疟区流动人口恶性疟原虫密度与发热等因素的多元线性回归分析

Multiple linear regression analysis of association of the Plasmodium falciparum density with fevers and age of malaria cases in mobile population in high malaria endemic areas in Yunnan Province

目的 探索恶性疟发热、年龄与原虫密度的关系。 方法 采用多元线性回归分析法分析 77例恶性疟发热、年龄与原虫密度的关系。 结果 对 77例恶性疟初发腋温 36.5～ 39.5℃的 67个病人进行分析 ,成人组 44人 ,初发恶性疟原虫密度与初发体温呈直线正相关关系 ,而与年龄无关。 (回归方程线性假设检验F =6.82 6,P <0 .0 5 ,回归方程 ^ Y=5 697.781x -2 12 5 71.1,相关系数r =0 .5 0 0 ,决定系数r2 =0 .2 5 0 )。儿童组 2 3人 ,初发恶性疟原虫密度与初发体温、年龄无相关关系。成人组和儿童组共复燃 34人 ,复燃恶性疟原虫密度与复燃体温、初发体温、初发原虫密度和年龄无相关关系。 (P >0 .0 5 )。 结论 在高疟区采用临床症状和体征辅助诊断和治疗时 。

Objective To investigate the relationship among fever,age and parasite density of plasmodium falciparum malaria cases. Methods Multiple linear regression was applied to analyze the relationship among fever,age and parasite density of 77 P.f malaria cases. Results The 67 P.f malaria cases with initial axillary temperature between 36.5 and 39.5 degree C in total 77 cases were analyzed.The initial parasite densities increased progressively with the increase of the inital axillary temperatures between 36.5 and 39.5 degree C of 44 P.f malaria cases in adult group,and no relationship with age.(Hypothesis testing of regression equation F=6.826,P<0.05. Regression equation ^Y=5697.781x-212571.1,r=0.500,r 2=0.250).Fcr 23 P.f malaria cases in child group,the initial parasite density did not relate to the initial temperature and age.There were totally 34 recrudescence cases in adult and child group,and the recrudescence parasite density did not relate to the recrudescence temperature,the initial temperature,the initial parasite density and age (P>0.05). Conclusion Microscopic examination of a blood slide should be considered as gold standard,when using clinical symptoms and physical examination to diagnosis and treat malaria cases in highly endemic areas.