女性生殖道解脲支原体感染对妊娠结局的影响

The consequence of Infection of Ureaplasma Urealyticum in the Pregnant Women

目的 调查妊娠期生殖道解脲支原体感染对孕产妇和新生儿的影响。方法 应用聚合酶链反应技术对妊娠期阴道分泌物测定 ,分成感染组和对照组进行结果分析。结果 2 430份阴道分泌物作解脲支原体的检测 ,检出阳性为 62 4例 ,妊娠中期感染率 2 4 5 3% ,晚期妊娠 2 8 86% ,总感染率为 2 5 68% ,解脲支原体有自然转阴性率为 74 5 1% (193/2 5 9) ,转阳性率为 15 2 1% (7/4 6)。解脲支原体感染中有胎膜早破 184例 (32 0 5 % ) ,明显高于对照组 2 0例 (2 2 % )P <0 0 5。对胎儿新生儿的影响主要为新生儿出生体重下降 ,感染组小于胎龄儿发生率明显高于对照组 (4 5 /5 74对 2 /10 0 ) P <0 0 5 ,围产儿死亡率感染组为 2 4 39‰并与对照组比较差别不明显 ,但明显高于同期分娩的围产儿死亡率 7 742‰ ,P值 <0 0 1。评分。结论 妊娠期感染解脲支原可引起胎膜早破增加 。

Objective To investigate influence of ureaplasma urealyticum(UU)infection on low genital tract during the pregnancy.The ureaplasma urealyticum was detected by the polymerase chain reaction(PCR) in women vaginal discharge. The patients were divided into infection group and control group.Results 624(25 68%) in 2430 cases of vaginal discharge had ureaplasma urealyticum infection. Infection rates of ureaplasma urealyticum was 24 53% in second trimester and 28 86% in third trimester respectively.184 cases (32 05%) of the premature rupture of membranes in infected group were significantly higher than 20 cases(22%) in control group. The UU infection incidence in small for gestation(SGA) age was increased in the infection group (45/574 vs 2/100)P<0 05. Conclusions The premature rupture of membranes and low fetal age of newborn was associated with infection of ureaplasma urealyticum in pregnancy.