甲减性贫血患者血清中SF、FA、VB_(12)的水平及临床意义

Clinical Significance of the Variation of Serum Levels ofSF、 FA、 VB_(12) in Patsents with Hypothyroidism Complicated with Anaemia

目的 :探讨铁蛋白 (SF)、叶酸 (FA)、维生素B12 (VB12 )在鉴定甲减性贫血的应用价值。方法 :采用化学发光免疫测定法对 73例甲减性贫血患者 ,4 0例对照组的血清进行SF、FA、VB12 的测定。采用阻抗法对全血细胞进行分析。结果 :病例组与对照组比较 ,SF、FA、VB12 含量均明显降低 ,两者有显著性差异 (p <0 0 1)。结论 :检测血清中SF、FA、VB12 的含量 ,并结合全血细胞的分析 ,对甲减性贫血类型的鉴别有较高的临床价值。

Objective To study the significance of changes of serum levels of ferritin (SF), folic aeid (FA) and vitamin B 12 (VB 12 ) in hypothyroidism patients complicated with anaeinia. Methods Serum SF, FA and VB 12 contents were determined with CLIA in 73 hypothyroidism patients and 40 controls. Whole blood analyses were performed with impedance method. Results In the diseased graup, SF, FA and VB 12 levels were significantly lower than those in the controls ( p <0 01). Conclusion Determination of SF, FA, VB 12 levels combined with whole blood analysis in those patiants might be helpful in defining the type of anaemia and could passibly save the patient from bone marrow puncture.