2Susan C, Louis M, Vivian F. Hyperhomocysteinemia-an emerging and important risk factor for thromboebolic and cardiovascular disease. Clin Chem, 1996,106:709-722
3Jacob S, Paul FJ, Peter WF, et al. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA, 1993,270:2693-2698.
4Drzewoski J, Czupryniak L, Bud E. Total plasma homocysteine and insulin levels in type 2 diabetic patients with secondary failure to oral agents. Diabetes Care, 1999,22:2097-2103.
5Lee WJ, Chen YT, Shen WH. Plasma homocysteine concentrations and insulin sensitivity in hypertensive subjects. Am J Hypertens, 2000,13(1 pt):14-20.
6House JD, Jacobs RL, Stead LM, et al. Regulation of homocysteine metabolism. Adv Enzyme Regul, 1999,39:69-91.
3Poirier L A, Brown AT, Fink LM, et al. Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy [ J ]. Metabolism, 2001,50(9) :1014-1018.
4De Bree A, Verschuren WM, Kromhout D, et al. Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease [ J ]. Pharmacol Rev, 2002,54 ( 4 ) : 599-618.
5Bautista LE, Arenas IA, Penuela A, et al. Total plasma homocysteine level and risk of cardiovascular disease; a metal-analysis of prospective cohort studies [ J]. J Clin Epidemiol,2002,55 (9) :882-887.
6Ni M,Zhang XH,Jiang SL,et al. Homocystinemia as an independent risk factor in the Chinese population at a high risk of coronary artery disease [ J ]. An, J Cardiol,2007,100 (3) :455-458.
7Toole JF, Malinow MR, Chambless LE, et al. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infaretinn,and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial [ J ]. JAMA, 2004,291 ( 5 ) : 565- 575.
8Becker A, Henry RM, Kostense PJ, et al. Plasma homocysteine and Sadenosylmethionine in erythrocytes as determinants of carotid intimamedia thickness:different effects in diabetic and non-diabetic individuals [ J ]. Atherosclerosis, 2003,169 ( 2 ) :323 -330.
9SHUKLA N,THOMPSONC S, ANGELINIG D, et al. Homocys-teine enhances impairment of endothelium-dependent relaxation and guani- dine cyclic monophosphate formation in aortae from diabetic rabbits [ J]. Diabetologia,2002,45 : 1325 - 1331.
10Mattock MB, Keen H, Viberti GC ,et al. Coronary heart disease and u- rinary albumin excretion rate in type 2(non-insulin-dependent) diabet- ic atients[ J]. Diabetologia, 1988,31 ( 2 ) :82 - 87.
