慢性乙型肝炎患者并发医院感染危险因素研究

Study on Risk Factors of Nosocomial Infection in Patients with Chronic Hepatitis B

目的:探讨慢性乙型肝炎患者与医院感染的关系,进一步研究分析慢性乙型肝炎发生医院感染的危险因素。方法:以1年来在襄樊市第一人民医院肝病科住院的慢性乙型肝炎患者为研究对象。采用病例对照研究的方法,就其并发医院感染的临床特点与慢性乙型肝炎的关系进行分析研究。结果:慢性乙型肝炎患者医院感染率为26.5％,高于我国的平均医院感染率9％。感染部位以呼吸道和腹腔感染为主;病程越长,病情越重,医院感染率越高;运用组胺H_2受体拮抗剂与导尿术是导致医院感染的危险因素。结论:慢性乙型肝炎患者医院感染率高达26.5％,是由慢性乙型肝炎的临床特点决定的。

Objective: To study of the risk factors of nosocomial infection in patients with chronic hepatitis B. Methods: A retrorespective investigation of nosocomial infection in patients with chronic hepatitis B was used, and the relationship between their clinical characteristic and nosocomial infection was studied. Results: The nosocomial infection rate in the patients with chronic hepatitis B (26.5%) was much higher than the average value (9%) in general patients. The respiratory tract and abdomen were the main infection sites. The high nosocomial infection rate in the patients with chronic hepatitis B was related with long periods of hospitalization, the severer state of the illness, the application of drugs of anti-H2 receptor and urine catheterization. Conclusion: Chronic hepatitis B patients resulted, in a higher nosocomial infection rate 26.5% in their hospitalization and many factors were involved in their nosocomial infection.