纤维蛋白原与丙肝病毒不同基因标志物检测的相关性探讨

Correlation between Fibrinogen and Variable Gene Marker of HCV

目的:探讨丙肝病毒(HCV)不同基因片段标志物的阳性结果与纤维蛋白原含量的关系。方法:HCV不同基因片段标志物测定用ELISA法,纤维蛋白原(Fbg)含量测定用磁珠搅拌法。结果:HCV结构区和非结构区 全部呈现阳性反应伴有Fbg含量明显降低。结论:两区全部呈现阳性反应并伴有Fbg明显降低者预示病情有进一步恶化的可能。

Objective: To study the relationship between fibrinogen and positive results of variable gene fragment marker of HCV. Methods: variable gene fragment marker were measured by ELISA methood, and fibrinogen were measured by magnetic bead stirring method. Results. The positive results of structual region and non - structual region of HCV correlated with the decrease of fibrinogen. Conclusion. The positive results of HCV with a decrease of fibrinogen indicate the possible, malignization of thd disease.