他汀类药对动脉粥样硬化病变中细胞粘附分子表达的影响
被引量：2
摘要
新近研究证明 ,在动脉粥样硬化发展的各个阶段炎症活动起根本作用 ,大量细胞粘附分子参与了这一炎症过程。他汀类药独立于降脂之外的抗炎作用也被逐渐认识 ,本文就他汀类药对动脉粥样硬化病变中细胞粘附分子影响的研究作一综述。
出处
《实用心脑肺血管病杂志》
2003年第2期109-112,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
参考文献24
-
1[1]Libby P,Ridker PM,Maseri A.Inflammation and atherosclerosis.Circulation.2002,105(9):1135～1143.
-
2[2]Milita Crisby,Gunilla Nordin-Fredriksson,Prediman K,et al.Pravastatin treatment increases collagen content and decreases lipid content,inflammation,Metalloproteinases,and cell death in human caroid plaques.Circulation.2001,2:926～933.
-
3[3]Carlas T.M,Harlam.J.M.Leukocyte-endothelial adhesion molecules. Blood. 1994,84:2068～2101.
-
4[4]Plutzky J.Inflammatory pathways in atherosclerosis and acute coronary syndromes.Am J Cardiol.2001,88(8A):10K～15K.
-
5[5]Muler WA,Randolph GJ.Migration of leukocytes across endothelium and beyond:Molecules involved in the transmigiration and fate of monocyte.J Leukoc Biol.1999,66:698～704.
-
6[6]Paston RN,Haskard DO,Couther JR,et al.Expression of intercellular adhesion molecule-1 in atherosclerotic plaques.Am J Pathol.1999,140:665～673.
-
7[7]Anne Hackman.,Yasunori Abe.Levels of soluble adhesion in patients with dyslipidemia.Circulation.1996,93:1334～1338.
-
8[8]Link A,Bohm M,Nickenung G..Acute coronary syndrome-better risk stratification by determination of inflammtation parameters? Med Klin.2002,97(2):63～69.
-
9[9]Bermudez EA,Ridker PM.C-reactive protein,statins,and the primary prevention of atherosclerotic cardiovascular disease.Prev Cardiol.2002,5(1):42～46.
-
10[10]Onno J.de Boer,Allard C,Peter Teeling,et al.Leucocyte recruitment in rupture prone regions of liopid-rich plaques:a prominent role for neovascularization? Cardiovascular Research.1999,41:443～449.
同被引文献24
-
1张莉峰,刘运海,杨期东,刘青芳.急性脑梗死患者颈动脉粥样硬化斑块的研究[J].卒中与神经疾病,2005,12(3):135-137. 被引量：25
-
2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量：33004
-
3张绪清,顾长海.细胞间粘附分子─1与肝病[J].中华肝脏病杂志,1997,5(2):110-112. 被引量：9
-
4Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet, 1998,351 (9113) : 1379-1387.
-
5Serrano C V, Yoshida V M, Venturinelli M L, et al. Effect of simvastatin monocyte adhesion molecule expression in patients with hypercholesterolemia. Atherosclerosis.2001,157:505-512.
-
6Muech AO, Seeger H, Wallwiener D. Further evidence for direct vascular actions of statins: effects on endothelial nitric oxide synthase and adhesion molecules. Exp Clin Endocrinol Diabetes,2001,109 : 181-183.
-
7Chung HK, Lee IK, Kang H, et al. Statin inhibits interferon-γ-induced expression of intercellular adhesion molecule-1 (ICAM-1) in vascular endothelial and smooth muscle cells. Exp Mol Med, 2002,34:451-461.
-
8Anderson ME, Siahaan TJ. Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: designing peptide and small molcule inhibitors. Peptides,2003,24 : 487-501.
-
9Kallen J, Welzenbach K, Ramage P, et al. Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain. J Mol Biol, 1999, b292 : 1-9.
-
10Weitz-Schmidt G, Welzenbaeh K, Brinkmann V, et al. Stadns selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. Nat Meal,2001,7:687-692.
二级引证文献5
-
1周冬梅,徐重白.颈动脉粥样硬化斑块的中医药治疗现状[J].中国中医急症,2010,19(11):1934-1935. 被引量：5
-
2王洋,雷燕.中医药治疗颈动脉粥样硬化研究进展[J].中国医药科学,2012,2(9):54-56. 被引量：6
-
3程广清,李长生,杨晓妮.化瘀通脉方治疗颈动脉粥样硬化斑块的临床观察[J].中国基层医药,2014,21(17):2561-2563. 被引量：1
-
4赵丽娟.他汀类调血脂药研究现状的综述[J].内蒙古中医药,2008,27(12X):62-64. 被引量：6
-
5顾梦平,伊桐凝.中医药治疗2型糖尿病合并颈动脉斑块的研究进展[J].中国现代医生,2024,62(5):126-128.
-
1翟衍志.美托洛尔与他汀类药联合治疗心肌梗死的临床疗效[J].健康导报（医学版）,2015,20(3):94-94.
-
2张雪梅.美托洛尔与他汀类药联合应用于临床分组治疗心肌梗死疗效对比分析与系统评价[J].大家健康（学术版）,2015(16):136-137. 被引量：6
-
3韩秀霞.他汀类药物对冠状动脉疾病患者C反应蛋白的作用[J].国外医学情报,2000(4):32-32.
-
4刘淑芬.糖尿病肾病的护理干预[J].中国社区医师（医学专业）,2011,13(17):269-269. 被引量：1
-
5刘海华,李爱静.C-反应蛋白与冠心病的相关性[J].华北煤炭医学院学报,2005,7(1):55-56.
-
6王伟明,韩福建,邱洪兵,丁幸辉.美托洛尔(倍他乐克)与他汀类药联合治疗心肌梗死的临床疗效分析[J].北方药学,2017,14(1):44-45. 被引量：4
-
7梁利波,王抒,黎健.载脂蛋白A-I对内皮细胞粘附分子表达的影响[J].中华医学杂志,2000,80(6):468-469. 被引量：3
-
8张波,刘树芬,张劭夫,齐法莲,孙文杰.哮喘患者细胞粘附分子表达及血浆可溶性E-选择素、P-选择素含量变化研究[J].中华内科杂志,1997,36(3):199-200. 被引量：2
-
9马湘俊.调脂治疗在冠心病防治中的新观点与现状[J].中华国际医学杂志,2001,1(4):344-346.
-
10孙凌云,张杏书.细胞粘附子的风湿性疾病[J].风湿病学杂志,1997,2(1):35-38. 被引量：3
