不同穴位配伍针刺对消化性溃疡患者血浆内皮素的影响

The Influence of Various Pairing of Acupoint on Plasma En- dothelion of Patients Suffering from Peptic Ulcer

目的:观察比较中脘、胃俞配伍和公孙、内关配伍针刺治疗消化性溃疡患者血浆内皮素(ET)水平的变化。方法:将50例消化性溃疡患者随机分为中脘、胃俞配伍和公孙、内关配伍2组进行针刺,均采用捻补法及小幅度震颤治疗,观察治疗前后血浆ET水平。结果:中脘、胃俞配伍组治疗后血浆ET水平分别为(78.42±6.74)ng/L、(50.11±3.49)ng/L,治疗前后比较差异有显著性意义(P<0.01)。公孙、内关配伍组治疗前后血浆ET水平分别为(80.13±8.59)ng/L、(48.32±4.73)ng/L,治疗前后比较差异有显著性意义(P<0.01)。2组间治疗后比较,差异光显著性意义(P>0.05)。结论:中脘、胃俞俞募配伍法及公孙、内关配伍针刺治疗消化性溃疡获效可能与ET变化有关,但2种不同配伍方案对疗效和ET变化的影响没有差异。

Objective: To compare the level of plasma endothelion (ET) in cases of peptic ulcer after needling Zhongwan (RN 12) -Weishu (BL 21) pairing and Gongsun (SP 4) -Neiguan (PC 6) pairing. Methods: 50 cases of peptic ulcer were allocated to Zhongwan - Weishu group (ZWG) and Gongsun - Neiguan group (GNG) randomly. The acupuncture was accomplished by twirling reinforcing manipulation with small amplitude of vibration. Plasma ET level was detected before and after treatment. Results: The plasma ET levels were (78. 72 ±6. 74) ng/L and (50. 11 ±3.49) ng/L before and after treatment ( P < 0. 01) in ZWG, and (80. 13± 6. 59) ng/L and (48. 32 ±4. 73) ng/L respectively ( P < 0. 01) in GNG. There was no statistical significance between two groups after treatment (P > 0,05) .Conclusion: Needling of Shu - Mu pairing (Zhongwan -Weishu) and (Gongsun - Neiguan) pairing is effective for peptic ulcer, which may be related with the change of ET, but the effectiveness and change of ET level show no significant difference between two kinds of pairing.